Bio Complete 3 Review: A Unique Probiotic for Gut Health (2024)

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  • Key Takeaways (TL;DR)
  • Bio Complete 3 at a Glance
  • The Cost
  • The Research
  • Safety Considerations
  • Alternatives

Key Takeaways (TL;DR)

  • Bio Complete 3 contains probiotics, prebiotics, and postbiotics, making it a fairly unique probiotic supplement.
  • Its ingredients have a good amount of scientific evidence (especially Baccillus Coagulans) showing their benefit in improving gut health and supporting energy levels.
  • Although this product may promote weight management, it should not be considered a solution for that goal.
  • The ingredients in this product are generally considered safe for healthy people. (See safety section for exceptions.)
  • Bio Complete 3 may be an excellent option for your daily regimen if you find yourself struggling to eat a balanced diet and need support managing a healthy gut.
  • To see results, it is best to take this product consistently. Evidence suggests that taking your probiotic for at least a few months will yield the most benefits, as it takes some time for the healthy bacteria to build up in your body.
  • If you’re unsatisfied, you can return Bio Complete 3 for a refund through the company’s 90-day money-back guarantee.

What Bio Complete 3 Gets Right

  • Offers probiotics, prebiotics, and postbiotics in one supplement.
  • The supplement contains ingredients that have been clinically studied and shown to be effective in improving gut health.
  • Has a 90-day money-back guarantee, even on opened products.

Important Considerations

  • The brand does not list probiotic CFUs per serving, making it impossible to know if the product contains an effective dose.
  • Other key ingredients have promising benefits but are in smaller amounts than what was studied, so they may be underdosed.
  • You must use this product consistently to see results, so consider the ongoing monthly costs.
  • Bio Complete 3 is more expensive than its competitors. But if using the subscription service and buying in bulk, the cost is similar to alternative products.
  • Having to take four capsules a day may not be appealing to some.

Bio Complete 3 at a Glance

Bio Complete 3 from GundryMD is a probiotic supplement created by Dr. Steven Gundry, a cardiac surgeon with over 30 years of experience. It is uniquely designed to support gut health by providing a blend of research-backed probiotics, prebiotics, and postbiotics.

One of the keys to optimal health lives in our gut. Research shows that the microbes living in our intestines interact significantly with our mind, heart, and overall wellness. Ensuring optimal gut health is essential for anyone wanting to take steps towards improving their overall health.

Bio Complete 3 aims to promote total body wellness by offering a comprehensive product to improve your gut health.

How to Take It

The recommended dosage for Bio Complete 3 is two capsules twice per day, taken before meals. For optimal benefits, it is recommended to take this product daily.

Tip: Combine Bio Complete 3 with a well-balanced diet and healthy lifestyle. Include plenty of fiber-rich foods such as whole grains, fruits, and vegetables. Add probiotic-containing foods such as kefir, Greek yogurt, and fermented vegetables to help maintain optimal gut health.

Click to View Supplement Facts

Bio Complete 3’s nutrition information per serving (4 capsules) includes:

  • Calories: 10
  • Total Fat: 1 gram
  • Saturated: 1 gram
  • CoreBiome (Standardized to 30% Tributyrin): 1000 mg
  • SunFiber™: 200 mg
  • ProDURA (Baccillus Coagulans): 16 mg

Other ingredients include Microcrystalline Cellulose, Hydroxypropyl Methylcellulose, Sunflower Oil, Fatty Acids Esterfied with Glycerol, Magnesium Stearate, Silica, Maltodextrin.

The Cost Is Not Cheap

Bio Complete 3 is not sold in stores and must be purchased directly online from the Gundry MD brand.

One-Time Purchase

Subscription

1 Bottle (30-day supply)

$69.95

$49.95

3 Bottles (90-day supply)

$188.85 ($62.95 per bottle)

$134.85 ($44.95 per bottle)

6 Bottles (180-day supply)

$353.70 ($58.95 per bottle)

$254.85 ($42.48 per bottle)

Supplements containing prebiotics, probiotics, and postbiotics are typically more expensive than products that only offer probiotics. Still, the one-time purchase price of Bio Complete 3 is more expensive than its competitors. However, buying it through a subscription makes a meaningful difference and makes the price comparable to alternatives.

The brand offers a friendly 90-day money-back guarantee, including for opened products. If you are not fully satisfied with your purchase, you may request a refund minus the shipping cost.

Try Bio Complete 3

Research Behind the Benefits of Bio Complete 3

Although Bio Complete 3 has not been tested as a whole, the supplement contains probiotics, prebiotics, and postbiotics that may help support your gut health and overall wellness. However, it’s important to remember that while certain ingredients produced some early promising results, they are used in smaller amounts in this supplement.

Additionally, the brand does not disclose how many CFUs are available per serving for Bacillus coagulans, which would be helpful considering there is solid research behind this probiotic strain.

Note: CFU stands for Colony Forming Units, representing the number of live and active microorganisms in one serving of a probiotic supplement.

Below we’ll break down the research behind ingredients and their possible roles in providing potential benefits.

Gut Health

Probiotic supplementation in healthy adults may improve the concentration of beneficial gut bacteria, leading to improved digestion, better bowel movements, and less gas and bloating.(1)

Research has found that the probiotic bacillus coagulans can withstand the stomach’s acidic environment to reach the intestine where it grows. Once B. coagulans is active in the small intestine, it will improve the groups of beneficial bacteria, resulting in better digestion, less abdominal pain, and less bloat.(2)

Bio Complete 3 also includes SunFiber, a prebiotic that positively affects digestive health and promotes better stool frequency and consistency. However, studies show that while it is promising, the amount of SunFiber in this supplement is significantly smaller than what was researched.(3)

Energy Support

Studies show that healthy bacteria in the gut are correlated with improved energy. Specifically, the probiotic B. coagulans used in Bio Complete 3 has been shown to aid in the digestion of carbohydrates and protein, allowing the body to utilize nutrients better, which may lead to improved energy.(4, 5)

Food Cravings

Studies have shown that having a positive balance of gut bacteria may lead to fewer cravings and food addictions.(6, 7)

Specifically, SunFiber™ is a soluble dietary fiber made from hydrolyzed guar gum that provides a feeling of fullness, possibly reducing cravings. However, the amount in Bio Complete 3 appears smaller than what was studied.(8)

Weight Management

Research has shown B. coagulans may play a role in the digestion of carbohydrates and protein, maximizing the benefits of protein supplementation. Optimal protein intake and absorption are necessary for weight loss.(5, 9)

Additionally, as mentioned earlier, SubFiber, a soluble fiber, may increase feelings of fullness by improving the good bacteria in your gut and overall digestion, resulting in healthy weight support.(7)

Finally, this supplement also contains Tributyrin, which studies show may play a small role in improving fat metabolism. However, more human research is needed as some studies have been done on animals.(10, 11)

Bio Complete 3 Review: A Unique Probiotic for Gut Health (1)

Consider Safety Before Taking This Supplement

Probiotics such as Bio Complete 3 are generally safe for healthy adults.

While not widely reported, some people may deal with mild side effects from most probiotic supplements, such as diarrhea and bloat, especially when you first start taking them.

However, caution should be used with taking probiotics if:

  • You have a weakened immune system, a critical illness, or have recently had surgery. This is due to a possible risk of infection in certain people.(12, 13)
  • You suffer from GI conditions. Before beginning supplementation, you should review with your physician, as some probiotics may worsen your condition.
  • You are pregnant or nursing. Bio Complete 3 is not intended for pregnant or nursing individuals without doctor supervision.

Bio Complete 3 is gluten-free, vegetarian, and free of added sugars. It has also been third-party tested to ensure purity and potency.

How Bio Complete 3 Compares to Alternatives

Bio Complete 3 is unique by containing prebiotics, probiotics, and postbiotics in its formula. Not many brands offer this combination of ingredients.

The more common ones are synbiotics, which refer to products that contain both prebiotics and probiotics. Seed Daily Synbiotic and Ritual Synbiotic+ are the two best brands we evaluated. Here’s how Bio Complete 3 compares to them.

Bio Complete 3

Seed Daily Synbiotic

Ritual Synbiotic+

3-in-1 (prebiotic, probiotic, and postbiotic)

Probiotic Strains

1

24

2

Clinical Studies

Third-Party Tested

Form & Daily Dosage

4 Capsules

2 Capsules

1 Capsule

Vegan

Subscription Price (30-day supply)

$49.95

$49.99

$54.00

Money-Back Guarantee

90 days

30 days

30 days

Expand to See How This Supplement Compares to These Brands

Vs. Seed Daily Synbiotic

If you are looking for a comprehensive probiotic supplement, Seed Daily Synbiotic is a solid choice.

It contains a blend of 24 clinically-studied probiotic strains and a prebiotic and has been shown to support the following:

  • Digestive health
  • Skin health
  • Nutrient synthesis
  • Heart health

Compared to Bio Complete 3, Seed clearly discloses the probiotic amounts, has undergone more thorough testing, and includes a broader range of probiotic strains for additional health benefits. However, Seed does not contain postbiotics.

Unlike Bio Complete 3, Seed also has a “capsule within a capsule” design to ensure the probiotics are alive when they arrive in your large intestine, so they’re most effective.

Read Our Full Seed Review

Vs. Ritual Synbiotic+

Just like Bio Complete 3, Ritual Synbiotic+ provides a blend of probiotics, prebiotics, and postbiotics to support gut health similarly.

It includes two strains of probiotics with amounts disclosed and has clinical trials to support their benefits.

Ritual also offers a delayed-release capsule to ensure the probiotics reach your intestines, which Bio Complete 3 lacks.

Read Our Full Ritual Synbiotic+ Review

Bio Complete 3 Review: A Unique Probiotic for Gut Health (2)

Try Bio Complete 3

Bio Complete 3 is a unique probiotic supplement that’s backed by research to promote digestive health. It’s also backed by a 90-day money-back guarantee for extra peace of mind.

Bio Complete 3 Review: A Unique Probiotic for Gut Health (2024)

FAQs

What are the side effects of taking Bio Complete 3? ›

It has methyl cellulous [also used in eye drops] which causes bloating, microcrystalline [which causes gas, bloating, depression, forgetfulness, lack of energy, and headaches], and maltodextrin [which is a sugar substitute that has tons of articles debating whether it's safe or not].

What does Bio Complete 3 do for the body? ›

Bio Complete 3 from Gundry MD is a comprehensive gut health supplement that combines prebiotics, probiotics, and postbiotics. The formula aims to help support your digestive system, promote weight management, enhance energy levels, and reduce unhealthy food cravings.

Is Gundry MD Bio Complete 3 FDA approved? ›

The ingredients in Bio Complete 3 all have GRAS (“Generally Recognized as Safe”) status from the FDA, with the exception of Bifidobacterium bifidum UABb-10 in the probiotic blend.

What is the best probiotic to improve gut health? ›

Some of the most frequently studied and recommended probiotics include:
  • The Lactobacillus genus, including L. acidophilus, L. rhamnosus, L. casei and L. plantarum.
  • The Bifidobacterium genus, including Bifidobacterium longum and Bifidobacterium breve.

Why do cardiologists warn against probiotics? ›

But, when it comes to pre-and probiotics, cardiologists are warning they aren't a treatment for elevated blood pressure, cholesterol, or other heart health markers. The health benefits of probiotics are also strain-specific, so taking any probiotic off the shelf won't guarantee results.

Who should not take probiotics? ›

Some reports have linked probiotics to serious infections and other side effects. The people most likely to have trouble are those with immune system problems, people who've had surgery, and others who are critically ill. Don't take probiotics if you have any of those issues.

What is the best probiotic for weight loss? ›

Ritual Synbiotic+ tops our list for best probiotic for weight loss overall. Ritual takes a comprehensive approach with their 3-in-1 supplement that includes prebiotics, probiotics, and postbiotics for total gut health. It's vegan friendly, gluten-free, third-party tested, and requires no refrigeration.

What meds do probiotics interfere with? ›

Some medications that may interact with certain probiotics include: antibiotics, antifungals (such as clotrimazole, ketoconazole, griseofulvin, nystatin).

What foods did Dr. Gundry quit? ›

LIST OF LECTIN-CONTAINING FOODS. The “No List” is a list of foods that are high in lectins. GRAIN OR SOYBEANS-FED FISH, SHELLFISH, POULTRY, BEEF, LAMB, AND PORK.

What vitamin D does Dr. Gundry recommend? ›

Vitamin D3 is essential for a lot of things, but most importantly, it is excellent at preventing viral infections. According to Dr. Gundry, it's even better than vitamin C at preventing you from getting sick! And you don't get enough of it from the sun.

What is the best women's probiotic to take? ›

Ritual Synbiotic+ stands out as the best probiotic for women because its unique formula combines probiotic strains clinically studied to support women's health. Plus, each delayed-release capsule contains prebiotics and postbiotics, whereas other supplements only contain probiotics.

Should a 70 year old woman take probiotics? ›

We often recommend that clients consider the health benefits of probiotics for seniors. While it's important to discuss any dietary changes with a qualified physician, many older adults benefit from helpful microbes that improve digestion and other bodily functions.

Do probiotics clean your colon? ›

Probiotics

Adding probiotics to your diet is another way to cleanse the colon. This also boosts overall health in many other ways. You can get more probiotics by taking probiotic supplements. Also, eat lots of probiotic-rich foods, like yogurt, kimchi, pickles, and other fermented foods.

Are there any side effects to taking probiotics? ›

Temporary digestive issues like gas and bloating are the most common side effects. If you have these, they tend to subside in a few weeks. To avoid any discomfort, it's a good idea to add probiotics to your diet gradually.

What are the side effects of bio D3? ›

In some cases, Bio-D3 Capsule can cause side effects like constipation or stomach upset, nausea, vomiting, loss of appetite, mood changes, weakness, tiredness, fast or pounding heartbeat, bone/muscle pain, and headache.

What are the effects of Bio 3? ›

This preparation presents a notable purgative action, very effective to regulate the intestinal function and to remove from the body fat and toxins , which can be harmful to the body. It also shows a powerful laxative action.

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